Genomic Instability
Changes and damage can accumulate within our DNA over time.
ScienceThe Science
12Hallmarks of Ageing ExplainedThe Science
of Healthy Ageing
Evidence-informed nutrition, a healthier lifestyle, and a deeper understanding of how we age.
At Althevity, we use science to guide practical choices, combining the biology of ageing, the power of everyday habits and thoughtfully formulated supplements.
One framework.
Many connected processes.
Ageing is complex.
It’s not driven by a single factor.
Scientists have identified interconnected biological processes known as the 12 Hallmarks of Ageing. They help us understand how our cells and systems change over time.
At Althevity, we use the 12 Hallmarks of Ageing as one of the scientific frameworks we consider when developing our formulations and exploring the science of healthy ageing.
The 12 Hallmarks of AgeingA framework for
A framework for
understanding ageing.
The hallmarks help illustrate how biological systems interact. They are not a checklist of finished-product benefits.
Telomere Attrition
Telomeres, the protective ends of chromosomes, can shorten as cells divide.
Epigenetic Alterations
The way genes are regulated and expressed can change throughout life.
Loss of Proteostasis
Our ability to maintain healthy, correctly functioning proteins can become less efficient.
Disabled Macroautophagy
Cellular processes responsible for removing and recycling damaged components can become less effective.
Deregulated Nutrient Sensing
Pathways that respond to nutrients and energy availability can change with age.
Mitochondrial Dysfunction
The mitochondria responsible for many aspects of cellular energy production can become less efficient.
Cellular Senescence
Some ageing or damaged cells stop dividing but remain metabolically active.
Stem Cell Exhaustion
The regenerative capacity of tissues can decline over time.
Altered Intercellular Communication
Communication between cells, tissues and biological systems can change with age.
Chronic Inflammation
Persistent low-grade inflammatory signalling is increasingly associated with ageing biology.
Dysbiosis
Changes in the composition and function of the microbiome may influence wider aspects of health and ageing.
Framework: López-Otín et al., Hallmarks of aging: An expanding universe (Cell, 2023)
More than supplementsHealthy ageing is a
Healthy ageing is a
whole-picture approach.
No supplement can replace the foundations of health. The choices we make every day matter across the lifespan.
Nutrition
A varied diet, rich in plant foods and fibre.
Movement
Regular activity that fits the way you live.
Sleep
Make time for restorative rest.
Stress Management
Space to pause, recover and reset.
Social Connection
Stay close to the people who matter.
Hydration
Water and everyday hydration habits.
Longevity, Simplified
Explore the resourcesScience, made more human.
Our approachScience-informed.
Science-informed.
Lifestyle-led.
Thoughtfully supplemented.
Clinical expertise, established nutritional science and evolving research, brought together with the habits that matter most.
Evidence-aware formulations
Ingredients selected with a clear scientific rationale.
Quality & transparency
Considered standards and independent laboratory testing.
Designed for real life
Simple routines that fit into everyday life.
This information is provided for educational purposes only and is not intended to diagnose, treat, cure or prevent any disease. Food supplements should not be used as a substitute for a varied, balanced diet and healthy lifestyle. Do not exceed the recommended daily intake. Keep out of reach of children. If you are pregnant or breastfeeding, taking medication, have a medical condition or are under medical supervision, consult an appropriate healthcare professional before use.